Desi Boyz started filming on 7 November 2010, and completed shooting in May 2011. The film was to feature Sonam Kapoor as the lead actress, but she declined the film. There were also rumours of the film being offered to Anushka Sharma, but she denied this. Eventually, Deepika Padukone and Chitrangda Singh were finalised as the female leads. Padukone will be seen opposite John Abraham for the first time and Singh will star opposite Akshay Kumar in her first commercial venture.

The world has been struck by the financial meltdown. But Jerry Patel (Akshay Kumar) and Nick Mathur (John Abraham) dont feel a thing in their comfortable pad in London. Nick feels smug with his successful investment banking job, the new bonus in his pocket and his beautiful fiancé, Radhika (Deepika Padukone), by his side. While Jerry is so used to scraping the bottom of the barrel and living off his best buddy Nick, that recession feels like home. But life has a way of pulling the rug from... Read More >>under our feet. Nick and Jerry stop smiling the day Nicks company decides to downsize and unceremoniously fires him. And Jerry is informed by the Social Services that his nephew Veer (Omi Vaidya), whom Jerry is local guardian to, will be placed in a foster home unless he gets a steady job.